摘要
观察复方大枣合剂(代号886甲)对可移植性小鼠乳腺癌(代号MA737)的生长抑制作用。方法:将MA737用小块法接种于近交系TA2小鼠腹股沟皮下,次日分别注射886甲、环磷酰胺、886甲+环磷酰胺及生理盐水隔日一次,共给10次,观察肿瘤抑制率和白细胞计数。结果:886甲对小鼠乳腺癌抑制率为59.89%,环磷酰胺为84.74%、886甲+环磷酰胺为88.70%,886甲组白细胞未见明显下降。结论:886甲对小鼠乳腺癌有一定抑制作用,对机体无毒副作用。
Objective: The inhibitory effects of the big jujubl mixture to the breast carcinoma of mice. Methods: The tissue of breast carcinoma of mice was transplanted into the inguinal subcuticle of inbreeding TA2 mice,the big jujubl mixture cyclophosphamidum and big jujubl mixture+ cyclophosphamidum were injected into the abdominal cavity from the second day after transplanting the breast carcinoma,and injected once every two days,in all ten times.The inhibitory rate of carcinoma and number of white blood cells were observed. Results: The inhibition rate of carcinoma in the groups of the big jujubl mixture cyclophosphamidum and big jujubl mixture+ cyclophosphamidum were 59.89%,84.74% and 88.70% respectively,the number of the white blood cells was not reduced obviously. Conclusion: The big jujubl mixture has the inhibitory effects on the breast carcinoma of mice and not toxinside effect to the whole body.
出处
《天津医科大学学报》
1999年第2期15-16,共2页
Journal of Tianjin Medical University
关键词
复方大枣合剂
乳腺癌
肿瘤抑制率
big jujubl mixture
breast carcinoma of mice
inhibiory rate of carcinoma