布比卡因复合芬太尼硬膜外阻滞用于分娩镇痛的临床研究

CLINICAL STUDY OF EPIDURAL ANALGESIA USING BUPIVACAINE WITH FENTANYL DURING LABOUR

观察布比卡因复合芬太尼硬膜外阻滞用于分娩镇痛的效果及对产程和母婴的影响。方法：对４５例初产妇随机分为３组：１组０．１２５％布比卡因，２组０．０６２５％布比卡因＋０．０００２％芬太尼，均采用持续硬膜外注药和病人自控给药。３组为对照组。结果：１、２组镇痛满意，两组间无差异；２组局麻药用量少，运动神经阻滞较轻，与１组比较差异显著。１、２组第２产程较３组明显缩短。第２产程时间、出血量和新生儿Ａｐｇｅｒ评分３组间无差异。结论：低浓度布比卡因复合小剂量芬太尼硬膜外阻滞为一安全、有效的分娩镇痛方法。

Objective: To observe the effects of epidural analgesia using bupivacaine with fentanyl on progress of labour, maternal and infantscondition Methods: Fourtyfive parturients were ramdomly allocated into three groups Group:0125% bupivacaine, group: 00625%bupivacaine/00002%fentanyl, using continuous epidural infusion and patientcontrolled epidural anaigesia (PCEA) ,group:controll group Results: Group and:pain relieved satisfactorily and had no significant difference in VAS; the dosage of local anaesthetic in groupwas less and moter block was ligther than in group; Duration of first stage of labour in groupandwas significantly shorter than in group However, there was no significant difference between the three group in the duration of the second stage of labour ,bleeding volume and Apgar scores Conclusion: Epidural analgesia with lower concentration of bupivacaine combined with lower dosage fentanyl is a safer and more effective analgesic method in labour