聚合磷酸钙骨水泥细胞毒性评价

Cytotoxic evaluation of polymeric calcium phosphate bone cements

目的：对自已合成的聚合磷酸钙骨水泥细胞毒性进行了研究。方法：将材料浸提液与小鼠成纤维细胞接触２、４、７ｄ后，用分光光度仪在５８８ｎｍ波长处测定吸光度，以评价材料的细胞毒性。结果：该材料细胞毒性为Ⅰ级，存在轻微的细胞毒性。

Aim: The cytotoxicity of polymeric calcium phosphate bone cement was studied. Method: After L929 mouse fibroblastic cells were expased to the material for 2,4 and 7 days, the optical absorbance was measured with ultraviolet spectrophotometer in 588 wavelength and the cytotoxicity of the material was evaluated. Results: There was slight cytotoxicity. Conclusions: The material is accordance with the biomaterial cytotoxicity for human implant.