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冠状动脉粥样硬化症及其危险因素的相关性研究 被引量:1

Relevant study on coronary artery atherosclerosis and its risk factors
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摘要 目的本研究对冠状动脉造影(CAG)结果显示冠脉血管直径狭窄<50%(冠状动脉粥样硬化症)与冠脉血管直径正常对比进行研究,分析冠状动脉粥样硬化症临床特点及其危险因素(年龄、吸烟、血脂、血压、血糖等)。方法比较分析冠状动脉造影示冠状动脉血管直径狭窄<50%和正常的冠心病患者200例。比较年龄、吸烟、高血压、高血脂、糖尿病病史,及9个月随访结果等临床差异。结果冠脉造影正常组年龄多<50岁,而<50%狭窄组年龄>50岁,差异有统计学意义。长期吸烟、高血压、糖尿病病史,冠脉造影<50%组较高,冠脉造影<50%组总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇及甘油三酯高于正常组。随访9个月后,冠脉造影<50%的患者发生心肌梗死、心力衰竭、心脏性死亡、总心血管事件较正常组偏高。结论冠脉造影<50%的患者多有吸烟史、年龄一般大于50岁,多有高血压、糖尿病、高血脂病史。 Objective This study compared coronary artery narrowing of 50% (coronary artery atherosclerosis) determined by coronary angiography (CAG) with coronary arteries of normal diameters and analyzed clinical features and the risk factors (age,smoking,blood lipids,blood pressure,blood glucose etc) of coronary artery atherosclerosis. Methods Comparatively analyzed 200 coronary artery disease patients having coronary artery narrowing (50%)suggested by CAG and those having normal coronary arteries. Clinical differences such as age,history of smoking,hypertension,hyperlipidemia,diabetes,and 9-month follow-up results were compared. Results Group of normal CAG results was mostly 50 years of age,the group of narrowing was 50 years old (50%),the difference was statistically significant. Histories of chronic smoking,hypertension,diabetes were more common in the CAG group (50%),Total blood lipids,low density lipoprotein,high density lipoprotein cholesterol,and triglyceride levels were higher in the CAG than the normal group (50%).Incidences of myocardial infarction,heart failure,cardiogenic death,total cardiovascular events were higher in patients with CAG(50%)than the normal group at 9 months follow-up.Conclusions Patients with CAG (50%) mostly had history of smoking,age span is usually above 50,and typically have history of hypertension,diabetes,and hyperlipidemia.
出处 《齐齐哈尔医学院学报》 2010年第15期2361-2362,共2页 Journal of Qiqihar Medical University
关键词 冠状动脉粥样硬化症 危险因素 冠状动脉造影 Coronary artery atherosclerosis Risk factors Coronary angiography
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