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持续性心房颤动患者血清脑利钠肽水平变化及对复律的影响 被引量:2

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摘要 目的观察持续性房颤患者血清脑利钠肽(BNP)水平的变化并探讨其与持续性房颤患者复律治疗后预后的关系。方法选取34例持续性房颤患者为房颤组和40例正常人群为对照组,检测两组人群的血清BNP。房颤组患者使用胺碘酮和电复律转复为窦性心律后随访3月,复律次日及随访结束时检测所有房颤患者的BNP。3月内复发的患者为复发组,维持窦律者为窦律组。回顾性分析两组患者的临床资料和血清BNP水平。结果房颤组患者血清BNP水平[(248.7±32.1)ng/L]明显高于对照组[(52.9±11.2)ng/L](P〈0.05)。34例房颤患者复律后随访3月,其中12例房颤复发,复发率为35.3%。复律前复发组患者BNP水平[(344.6±40.7)ng/L]显著高于窦律组[(139.9±21.7)ng/L](P〈0.05);复律后次日两组患者BNP分别为(84.2±12.3)ng/L、(77.9±15.6)ng/L,两组比较差异无显著性;随访3月后,复发组患者BNP水平[(269.2±24.1)ng/L]显著高于窦律组[(58.7±16.9)ng/L](P〈0.05)。结论持续性房颤患者血清BNP水平升高,且BNP水平与持续性房颤复律治疗的预后相关。
出处 《临床内科杂志》 CAS 2010年第9期630-631,共2页 Journal of Clinical Internal Medicine
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