摘要
目的测定健儿乐颗粒中芍药苷的含量。方法采用高效液相色谱法,色谱柱为C18柱(250mm×4.6mm,5μm),流动相为乙腈-0.1%磷酸溶液(14∶86),检测波长230nm。结果芍药苷进样量在0.1768～1.7680μg范围内与峰面积线性关系良好,加样回收率为98.60%,RSD为0.48%(n=6)。结论所用方法快速、准确,可作为健儿乐颗粒的质量控制方法。
Objective To determine the content of paeoniflorin in Jian＇erle Granules.Methods HPLC method was adopted and the C18 column（250 mm×4.6 mm,5 μm） was used.The mobile phase was acetonitrile-0.1%phosphoric acid（14 ∶86）.The detection wavelength was at 230 nm.Results The calibration curve of paeoniflorin was linear in the range of 0.176 8-1.768 0 μg（r=0.999 9）,the average recovery rate was 98.60%,RSD=0.48%（n=6）.Conclusion The method is quick and accurate,which can be used for the quality control of Jian＇erle Granules.
出处
《中国药业》
CAS
2010年第17期23-23,共1页
China Pharmaceuticals
