饮食管理在肝硬化晚期合并肝癌患者中的应用效果观察

目的探讨饮食管理在肝硬化晚期合并肝癌患者中的应用效果。方法将50例肝硬化晚期合并肝癌患者随机分为实验组(26例)和对照组(24例),两组患者均实施常规的护理,实验组患者在此基础上加强饮食管理。比较两组患者的临床症状、体征和生化指标变化情况的差异。结果实验组患者并发症发生率较对照组低,其中两组患者在肝性脑病、食欲不振、低血糖和乏力发生率比较,差异具有统计学意义。实验组患者白蛋白、前白蛋白都相应的比对照组高;而反映肝细胞破坏程度的2个指标:总胆红素和甲胎蛋白,结果则相反,对照组相对较高,经统计学分析,均P<0.05,差异具有统计学意义。结论对晚期肝硬化合并肝癌患者加强饮食管理可延缓疾病的进展,进而提高患者的生活质量。

Objective To investigate the effect of diet management late cirrhosis combined with liver cancer.Methods 26 patients with hepatic cirrhosis combined with liver cancer were assigned as experimental group receiving diet management and another 24 patients with the same pathogenic conditions as controls,receiving no diet control.The patients in both groups underwent supportive treatment symptomatically.Those in the experimental group received diet management while those controls did not.The two groups were compared in respect of clinical symptoms,physical signs and biochemical indicators.Results There were fewer cases that developed hepatic encephalopathy or contracted anepithymia,hypoglycaemia and hypodynamia in the experimental group than those in the control group.The levels of albumen and prealbumen in the experimental group were significantly higher than those of controls（P〈 0.05）,while the levels of total bilirubin and alpha fetoprotein were significantly lower（P〈 0.05）.Conclusions It is necessary to regulate the dieting nutrition among the patients with hepatic cirrhosis combined with liver cancer.Diet management may delay the process of liver cancer and so helps to increase the quality of life.