摘要
丙型肝炎病毒(HCV)是引起致死性肝病的主要原因,全球有1.7亿人感染。HCV基因高度变异,目前可被分为6个基因型,其亚型也在不断增加。缺乏有效的体外细胞培养系统限制了HCV病原学、复制机制和生命周期等方面的研究。
Hepatitis C virus（HCV） is the major cause of fatal liver diseases such as cirrhosis,liver failure,and hepatocellular carcimona. It is estimated that approximately 170 million people worldwide are persistently infected by HCV.It has a high genetic variability and is currently classified into six major genotypes and with an increasing number of subtypes.The study of pathogenesis,replication and the entire life cycle of HCV have been hampered by the lack of an efficient cell culture system.
出处
《中华疾病控制杂志》
CAS
2010年第7期664-667,共4页
Chinese Journal of Disease Control & Prevention
