舒利迭吸入治疗稳定期慢性阻塞性肺疾病70例

Efficacy of seretide in treating 70 cases of stable chronic obstructive pulmonary disease

目的观察舒利迭吸入治疗慢性阻塞性肺疾病(COPD)稳定期患者的疗效。方法将70例处于稳定期的中、重度COPD患者,随机分为治疗组和对照组。两组均给予常规治疗,在此基础上,治疗组给予吸入舒利迭(50/250),每次1吸,每天2次;对照组给予缓释茶碱片,每次0.1 g,每天2次,比较两组治疗前、后肺功能及临床症状积分变化。结果治疗后治疗组肺功能指标、临床症状积分改善情况均明显优于对照组(P<0.05)。结论对于稳定期COPD患者,舒利迭能减轻临床症状,明显改善肺功能,提高生活质量。

Objective To observe the effects of seretide on stable chronic obstructive pulmonary disease（COPD）.Methods Seventy patients with stable moderate and sever COPD were randomly divided into treatment group and control group.Two groups were given conventional treatment.The treatment group was given seretide（50/250,bid）,and the control group was given therophylline slow-releasing pill（0.1,bid） on the basis of conventional treatment.Both groups received 3-months inhalation treatment,lung function and clinical symptom scores between the two groups were compared before and after treatment.Results After treatment,the lung function and the clinical symptom scores of the treatment group were significantly higher than that of the control group（P0.05）.Conclusion Combined inhaled seretide in patients with stable COPD can relieve the clinical symptom and improve lung function and raise life quality.