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三阴乳腺癌临床特征分析 被引量:4

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摘要 目的了解三阴乳腺癌患者的临床特征。方法收集我院肿瘤科2003年3月至2005年3月2年间收治的乳腺癌手术患者的临床资料,其临床资料和随访资料完整者共728例,其中86例为三阴乳腺癌患者,通过与非三阴乳腺癌患者相比,分析患者的临床特点及5年生存率。结果三阴乳腺癌患者占所有乳腺癌患者的11.8%。绝经前女性多(60.5%);肿块较大,>5 cm者占27.9%(24例);淋巴结转移者多(58.1%);三阴乳腺癌复发转移,主要是肝转移和肺转移。5年总生存率为80.23%,低于非三阴性乳腺癌患者的90.03%。有淋巴结转移者复发率(76.0%)要低于无淋巴结转移者(86.11%)。结论与非三阴乳腺癌比较,三阴乳腺癌有不同的临床特点,复发转移以内脏(肺和肝)转移和脑转移多见,三阴乳腺癌的预后更差。
出处 《临床医学》 CAS 2010年第9期68-69,共2页 Clinical Medicine
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  • 1Sorlie T,Tibshirani R,Parker J,et al.Repeated observation of breast tumor subtypes in independent gene expression data sets[J].Proc Natl Acad Sci USA,2003,100(14):8418-8423.
  • 2Perou CM,Sorlie T,Eisen MB,et al.Molecularportraits of human breast tumours[J].Nature,2000,406(679):747-752.
  • 3Sorlie T,Perou CM,Tibshirani R,et al.Gene expression patterns ofbreast carcinomas distinguish tumor subclasses with clinical implications[J].Proc Natl Acad Sci USA,2001,98(19):10869-10874.
  • 4Foulkes WD,Stefansson IM,Chappuis PO,et al.Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer[J].Natl Cancer Inst,2003,95(19):1482-1485.
  • 5Cleator S,Heller W,Coombes RC.Triple-negative breast cancer:therapeutic options[J].Lancet Oncol,2007,8(3):235-244.
  • 6杨名添,戎铁华,黄植蕃,曾灿光,龙浩,傅剑华,林鹏,王欣,王思愚,王曦,唐军.可手术乳腺癌6263例临床分析[J].癌症,2005,24(3):327-331. 被引量:46

二级参考文献13

  • 1Nab HW, Hop WC, Crommelin MA, et al. Changes in long term prognosis for breast cancer in a Dutch cancer registry[J]. BMJ, 1994,309(6947): 83-86.
  • 2Rutqvist LE, Wallgren A, Nilsson B. Is breast cancer a curable disease? A study of 14,731 women with breast cancer from the Cancer Registry of Norway [J]. Cancer, 1984,53(8): 1793-1800.
  • 3Roses DF. Breast Cancer [M]. New York: Churchill livingstone, 1999: 312.
  • 4Maddox WA, Carpenter JT Jr, Laws HL, et al. A randomized prospective trial of radical (Halsted) mastectomy versus modified radical mastectomy in 311 breast cancer patients [J].Ann Surg, 1983,198(2) :207-212.
  • 5Turner L, Swindell R, Bell WG, et al. Radical versus modified radical mastectomy for breast cancer [J]. Ann R Coil Surg Engl, 1981,63(4) :239-243.
  • 6Martin JK Jr, van Heerden JA, Taylor WF, et al. Is modified radical mastectomy really equivalent to radical mastectomy in treatment of carcinoma of the breast? [J]. Cancer, 1986,57(3) :510-518.
  • 7Early Breast Cancer Trialists Collaborative Group. Effects of radiotherapy and surgery in early breast cancer [J]. N Engl J Med, 1995,333(22): 1444-1455.
  • 8Early Breast Cancer Trialists' Collaborative Group.Polychemotherapy for early breast cancer: an overview of the randomised trials [J]. Lancet, 1998,352(9132) :930-942.
  • 9Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomized Trials[J]. Lancet, 1998,351(9114): 1451-1467.
  • 10Fisher B, Jeong JH, Bryant J, et al. Treatment of lymphnode-negative, oestrogen-receptor-positive breast cancer: long term findings from National Surgical Adjuvant Breast and Bowel Project randomised clinical trials [J]. Lancet, 2004,364 ( 9437 ): 858-868.

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  • 1王玲,单保恩,张建彬.塞来昔布对人三阴性乳腺癌细胞MDA-MB-231迁移、侵袭及黏附性的影响[J].中国癌症杂志,2011,21(4):266-271. 被引量:15
  • 2Bauer K, Brown M, Cress R, et al. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)- negative, and HER2-negative invasive breast cancer, the so- called triple-negative phenotype: a population-based study from the california cancer registry[J]. Cancer, 2007, 109 (9) : 1721- 1728.
  • 3American Joint Committee on Cancer. AJJC Cancer Staging Manual[M]. 5th ed. Philadelphia (PA) : Lippineott-Raven, 1997..103-108.
  • 4Ktimmel A, Kiimmel S, Barinoff J, et al. Prognostic factors for local, coco-regional and systemic recurrence in early-stage breast cancerl-J3. Geburtshilfe Frauenheilkd, 2015,75 (7) : 710-718.
  • 5Finch AP, Lubinski J, Mller P, et al. Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation[J]. J Clin Oncol,2014,32(15) : 1547-1553.
  • 6Fulford LG, Easton morphological features DF, Reis-Filho JS, et predictive for the basal grade 3 invasive ductal carcinoma of al. Specific phenotype in breast [J]. Histopathology, 2006,49 (1) : 22-34.
  • 7Reis-Filho JS, Milanezi F, Steele D, et al. Metaplastic breast carcinomas are basal-like tumours[J]. Histopathology,2006,49 (1) :10-21.
  • 8Dent R, Trudeau M, Pritchard KI, et al. Triple-negative breast cancer: clinical features and patterns of recurrence[J]. Clin Cancer Res,2007,13(1):4429-4434.
  • 9Tischkowitz M, Brunet JS, B6gin LR, et al. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer[J]. BMC Cancer,2007,7 : 134.
  • 10罗忠兵,龙浩,马国伟,林志潮,司徒冬荣,杨名添,戎铁华.140例三阴乳腺癌病例分析[J].赣南医学院学报,2009,29(3):332-335. 被引量:9

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