摘要
目的研究岗梅Ilexasprella根的化学成分。方法采用硅胶、凝胶和RP-HPLC等色谱方法对岗梅根的化学成分进行分离纯化,并根据理化性质和波谱数据鉴定化合物的结构。结果从岗梅根的70%乙醇提取物中分离得到10个三萜及其皂苷类化合物,分别鉴定为28-O-β-D-glucopyranosyl pomolic acid（1）、冬青苷XXIX（ilexo-side XXIX,2）、冬青苷B（ilexoside B,3）、刺参苷F（monepaloside F,4）、长圆冬青苷B（oblonganoside B,5）、3-O-β-D-xylopyranosyl-3β-hydroxyurs-12,18（19）-dien-28-oic acid 28-β-D-glucopyranosyl ester（6）、毛冬青皂苷B（ilexsapo-nin B,7）、randialic acid B（8）、毛冬青酸（ilexolic acid,9）和19-去氢乌索酸（19-dehydroursolic acid,10）。结论化合物1~9均为首次从该植物中分离得到。
Objective To investigate the chemical constituents from the roots of Ilex asprella.Methods The chemical constituents were isolated by silica gel,Sephadex LH-20,as well as RP-HPLC column chromatography.Their structures were identified on the basis of physicochemical properties and spectral analysis.Results Ten triterpenes and triterpenoid saponins were isolated and identified as 28O-β-D-glucopyranosyl pomolic acid（1）,ilexoside XXIX（2）,ilexoside B（3）,monepaloside F（4）,oblonganoside B（5）,3-O-β-D-xylopyranosyl-3β-hydroxyurs-12,18（19）-dien-28-oic acid 28-β-D-glucopyranosyl ester（6）,ilexsaponin B（7）,randialic acid B（8）,ilexolic acid（9）,and 19-dehydroursolic acid（10）,respectively.Conclusion Compounds 1-9 are isolated from I.asprella for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2010年第9期1426-1429,共4页
Chinese Traditional and Herbal Drugs
基金
广东省自然科学基金团队项目(No.8351063201000003)
澳门特别行政区科学技术发展基金(No.013/2008/A1)
广东省科技计划国际合作项目(No.2008A050200005)
关键词
岗梅根
三萜
三萜皂苷
Ilex asprella（Hook.et Arn.） Champ.ex Benth.
triterpenes
triterpenoid saponins
