温度对WMO-1号液保存犬肾的影响

Effect of temperature on canine kidney preservation with WMO 1 solution

目的探讨温度对ＷＭＯ１号液保存犬肾的影响。方法采用保存自体移植模型，比较了不同温度条件下ＷＭＯ１号液保存犬肾２４小时后的肾功能和形态学变化。结果保存肾的损害程度与保存温度有关。１５℃保存２４小时不足以防止肾脏缺血损害，５～８℃组术后最大血肌酐值和平均血肌酐值均显著低于１～４℃组和９～１２℃组，形态学变化亦较轻。结论ＷＭＯ１号液保存犬肾的最适宜保存温度为５～８℃。

Objective To explore the effect of temperature on canine kidney preservation with WMO 1 solution. Methods Preservation autotransplanted model was used to compare the effect of preservative temperature on the function and morphology of the canine kidneys flushed with WMO 1 solution and stored for 24 h.Results The preserved renal damage was related to the preservative temperature. Storage at 15℃ could not prevent the renal damage from ischemia. The effective preservative temperature was 1℃～4℃ and 9℃～12℃. Preservation at 5℃ to 8℃ was the most suitable for canine kidney.Conclusion Lower or higher temperature might aggravate the renal injury.