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头孢曲松钠相关假性胆囊结石 被引量:1

Ceftriaxone sodium-related biliary pseudolithiasis
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摘要 1例48岁女性患者,因椎间盘突出伴右臂疼痛静脉滴注头孢曲松钠3g,1次/d,尼美舒利分散片0.1g,2次/d口服,复方氯唑沙宗2片,3次/d口服。用药5d后,患者出现恶心、呕吐、腹痛等症状。停用所用药物,给予莫沙比利、胃炎颗粒治疗4d无缓解,以腹痛待查入院。腹部超声检查:胆囊内约1.8cm×0.9cm泥沙样强回声光斑,肝内、外胆管未见扩张,考虑胆囊结石与头孢曲松钠有关。给予抗酸、解痉等对症治疗,7d后胆囊结石明显缩小,遂出院。1个月后超声复查未见结石。 A 48-year-old woman with intervertebral disk hernia and right arm pain received an IV infusion of ceftriaxone sodium 3 g once daily,dispersible nimesulide 0.1 g,twice daily and 2 compound chlorzoxazone tablets,three times daily. Five days later,the patient presented with nausea,vomiting and abdominal pain. Ceftriaxone sodium was discontinued. She was given mosapride and weiyankeli for 4 days with no improvement. The patient was hospitalized for abdominal pain. Abdominal ultrasonography showed 1.8 cm×0.9 cm echo-dense sand-like calculi in her gallbladder. No intra-or extrahapatic bile duct dilatation was seen. Cholecystolithiasis was considered to be related to ceftriaxone sodium. The patient received symptomatic treatment of antacid and spasmolysis. After seven days of the treatment,her calculi decreased in size and then she was discharged. One month later,no calculi were detected on repeat ultrasound examination.
出处 《药物不良反应杂志》 2010年第4期268-268,272,共2页 Adverse Drug Reactions Journal
关键词 头孢曲松钠 不良反应 假性胆囊结石 ceftriaxone sodium biliary pseudolithiasis
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参考文献5

  • 1Schaad UB, Wedgwood J, Tschaeppeler H. Reversile ceftriaxone-associated biliary pseudolithiasis in children. Lancet [J], 1988, 17(2):1411-1413.
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二级参考文献18

  • 1王永清.头孢曲松钠导致小儿假性胆石症一例[J].中华儿科杂志,2005,43(4):251-251. 被引量:20
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