摘要
1例44岁拟行子宫肌瘤切除术患者,为预防感染于术前5d开始给予阿莫西林6.0g溶于0.9%氯化钠注射液500mL中静脉滴注,1次/d。术后约15min患者出现血尿,SCr为140.99μmol/L。考虑急性肾衰竭与阿莫西林剂量过大有关。停用阿莫西林,改为头孢噻肟和美洛西林-舒巴坦,同时给予呋塞米、泮托拉唑。术后14d患者肾功能恢复正常。
A 44-year-old woman started receiving an IV infusion of amoxicillin 6 g dissolved in 500 mL of 0.9% sodium chloride once daily for preventing infection 5 days before undergoing hysteromyomectomy. On day 6,the patient developed hematuria 15 minutes after surgery,and serum creatinine level was 140.99 μmol/L. Acute renal failure was considered to be related to amoxicillin overdose. Amoxicillin was discontinued and switched to cefotaxime and mezlocillin-sulbactam. Meanwhile she was given furosemide,pantoprazole. On day 14 after surgery,the patient＇s renal function returned to normal.
出处
《药物不良反应杂志》
2010年第4期276-277,共2页
Adverse Drug Reactions Journal
关键词
阿莫西林
不良反应
过量使用
肾衰竭
amoxicillin
adverse reactions
overdosage
renal failure
