摘要
目的探讨乳腺血管外皮瘤/孤立性纤维性肿瘤(HPC/SFT)的病理学特点、诊断及鉴别诊断。方法对1例乳腺HPC/SFT进行临床病理、组织形态、免疫组化染色进行观察并复习文献。结果该病组织学特点为血管丰富,呈分支状,瘤细胞围绕血管呈放射状或弥漫排列,瘤细胞呈圆形、椭圆形和梭形,细胞界限不清。免疫组化染色vimentin、CD34、CD99和bcl-2均(+)。结论 HPC/SFT是少见的软组织肿瘤,发生在乳腺更为罕见,预后好。应根据形态学特点,结合免疫组化结果鉴别。
Objective To investigate the pathologic characteristics of hemangiopericytoma/solitary fibrous tumor ( HPC/SFT) in the breast, and its diagnosis and differential diagnosis from other tumors. Methods One case of HPC/SFT was observed with pathologic examination and the related literature was briefly reviewed. Results Histologically, this tumour showed an abundant vascular pattern forming a continuous ramifying network; the tumor cells had radiational or suffusive array around vessels, and appeared roundish, oval or fusiform with indistinct cell ambit. The tumor cells expressed vimentin, CD34, CD99 and bcl-2. Conclusion HPC/SFT is a rare soft tissue tumour in the breast, with good prognosis. So its correct diagnosis and differential diagnosis can be made with careful analyses of the histopathological and immunohistochemical data.
出处
《诊断病理学杂志》
CSCD
2010年第4期284-286,共3页
Chinese Journal of Diagnostic Pathology