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2型糖尿病患者空腹血浆皮质醇升高与缺血性心脏病及其危险因素相关:爱丁堡2型糖尿病研究 被引量:2

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摘要 在库欣综合征,过量的糖皮质激素可导致中心型肥胖、胰岛素抵抗、2型糖尿病、高血压以及其他心血管危险因素。最近的研究表明,血浆皮质醇的些微增加有可能使构成“代谢综合征”的心血管危险因素集中出现。已有研究报道在糖耐量异常、高血压和血脂异常患者中,清晨血浆皮质醇升高。一般认为这与下丘脑-垂体-肾上腺(HPA)轴的中枢调节改变有关。
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2010年第8期711-713,共3页 Chinese Journal of Endocrinology and Metabolism
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  • 1田敏,李友谊,吕红彬.糖基化终末产物及其受体与糖尿病视网膜病变的研究进展[J].眼科新进展,2013,33(12):1194-1197. 被引量:6
  • 2王晓辉,田浩明.2型糖尿病患者血浆皮质醇、游离脂肪酸水平和胰岛素抵抗[J].中华内分泌代谢杂志,2004,20(3):210-211. 被引量:12
  • 3Elahi-Moghaddam Z,Behnam-Rassouli M,Mahdavi-Shahri N,et al.Comparative study on the effects oftype 1and type 2diabetes on structural changes andhormonal output of the adrenal cortex in male Wistarrats.[J].J Diabetes Metab Disord,2013,12(1):9.
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  • 6Mo M, Zhong W, Zhao G, et al. Combining glycosylated hemoglobin AI c and fasting plasma glucose for diagnosis of type 2 diabetes in Chinese adults [ J ]. BMC Endocr Disord,2013,13 ( 1 ) :44.
  • 7Joseph N, Unnikrishnan B, Raghavendra B Y P, et al. Proportion of depression and its determinants among type 2 diabetes mellitus pa- tients in various tertiary care hospitals in Mangalore city of South In- dia[ J]. Indian J Endocrinol Metab ,2013,17 (4) :681-688.
  • 8Fatima A,Khawaja K I,Buraey S ,et al. Type 1 and type 2 diabetes mellitus : are they mutually exclusive [ J ]. Singapore Med J,2013,54 (7) :396-400.
  • 9Chcn X, Zhao Z, Chai Y, et al. Stress-dose hydrocortisone reduces critical illness-related corticosteroid insufficiency associated with se- vere traumatic brain injury in rats [ J ]. Crit Care, 2013,17 (5): R241.
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