重症急性胰腺炎的早期综合治疗

Early comprehensive therapy in patients with severe acute pancreatitis

目的探讨重症急性胰腺炎的早期综合治疗方法,以提高治愈率,降低并发症和死亡率。方法回顾分析28例重症急性胰腺炎的诊治过程,分析早期综合治疗的临床疗效。结果 24例治愈,4例死亡;连续性血液净化组早期临床表现改善明显。结论重症急性胰腺炎的早期个体化综合治疗尤为重要,早期阻断全身性炎症反应综合症的发生能明显改善患者的预后。

Objective To investigate the use of early comprehensive therapy in patients with severe acute pancreatitis（SAP） to reduce complications and fatality. Methods Retrospective study of 28 SAP patients with early clinical comprehensive therapy was investigated. Results Twenty-four patients recovered well and 4 patients died. The patients underwent continuous renal replacement therapy （CRRT） improved significantly in early clinical manifestation. Conclusion It is beneficial to apply early individual comprehesive therapy including CRRT in the treatment of patients with SAP. Early intervention of systemic inflammatory response syndrome can significantly improve the prognosis of SAP patients.