高压氧治疗外伤性脑梗死的疗效分析

Analysis of therapeutic effect of hyperbaric oxygen on traumatic cerebral infarction

目的分析外伤性脑梗死的发生机制、临床特征、高压氧辅助治疗的机制和临床治疗效果。方法 40例外伤性脑梗死随机分为高压氧治疗组20例和对照组(常规治疗组)20例,两组的治疗结果进行统计学对照分析。结果伤后6个月按照GOS预后计分评定两组治疗效果。高压氧治疗组良好率为45%(9例),对照组为20%(4例)。P<0.01差异显著,有统计学意义。结论外伤性脑梗死的发生机制与脑外伤后的占位效应、血管痉挛、血流动力学改变等因素有关。高压氧可提高血氧含量,改善微循环和血流动力学功能,纠正梗死灶的缺血低氧状态,促进神经功能恢复,提高预后良好率,降低伤残程度,是安全、有效的辅助治疗方法。

Objective To discuss the mechanism and clinical manifestation of traumatic cerebral infarction(TCI),and the therapeutic effect of hyperbaric oxygen on TCI.Methods Forty patients with traumatic cerebral infarction were randomly divided into hyperbaric oxygen treatment group and control group,20 patients in each group.The therapeutic effects of two groups were statistically analyzed according to GOS prognostic scoring system six months after injury.Results The good recovery rate was 45.00% in hyperbaric oxygen treatment group,20.00% in control group.There was significant difference between two groups.Conclusion The hyperbaric oxygen can improve cerebral micro-circulation and hemorheological index of cerebral infarction area,which is a safe and effective method in improving outcome and reducing disability in patients with traumatic cerebral infarction.