养阴抗毒法对兔肝癌射频治疗的影响

Effect of Yin antitoxic method effects on radiofrequency ablation of rabbit liver cancer

目的:观察养阴抗毒法对兔肝VX2移植瘤RFA术后反应的影响。方法:采用移植法建立兔肝移植瘤模型。分为4组:A组,预防组;B组,治疗组;C组,抗生素组;D组,空白组。在B超引导下行RFA治疗,术后1周处死动物并做肝组织病理切片在光镜下观察,检测治疗前后血常规及肝肾功变化。结果:A、B、C组肝组织病理切片可见细胞大量凝固性坏死,血常规、肝肾功变化有统计学意义(P<0.05);B、C组可见少量炎性细胞,以C组为甚。D组病理及实验检验指标无变化。结论:养阴抗毒法可以提高兔肝移植瘤RFA疗效并减轻或缓解对正常组织的损伤。

Objective：To observe the effect of Yin antitoxic liver VX2 tumor after RFA treatment.Methods：With transplantation tumor model of rabbit liver transplantation,rabbits were divided into 4 groups,A prevention group,B treated group,C antibiotic group,D control group.B ultrasound-guided RFA was used in the treatment of descending,animals were sacrificed after two weeks and to observe liver and kidney function before and after treatment.Results：A,B,C group showed a large number of cells,coagulation necrosis,liver and kidney function changes were statistically different,B,C groups showed a small amount of inflammatory cells.Group D had no change.Conclusion：Yin antitoxic method can improve the effects of radiofrequency ablation and radiofrequency ablation significantly reduce the damage of normal tissue.