Alzheimer基因研究现状

Research actuality of Alzheimer's disease gene

阿尔茨海默病(AD)目前临床无客观性生化检测手段,仅靠精神量表,且常在临床症状出现后才能诊断。近年来,一系列新的基因研究有助于阿尔茨海默病的早期识别。这些基因的改变往往先于阿尔茨海默病的病理变化和临床表现,对其早期诊断有重要意义。本文就这些基因的研究现状作一综述。

Currently,Alzheimer＇s disease（AD） has not the objectivity of clinical and biochemical detection methods,relying on the spirit of the scale,and often diagnosed only after symptoms appear.In recent years,a series of new genes research will help the early identification of Alzheimer＇s disease.Changes in these genes often precede Alzheimer＇s disease pathology and clinical manifestations,its early diagnosis is important.This paper present the research actuality in these genes are reviewed.