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新型口服抗血小板活化和聚集药物——普拉格雷 被引量:4

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出处 《中国药学杂志》 CAS CSCD 北大核心 2010年第17期1357-1358,共2页 Chinese Pharmaceutical Journal
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  • 1FARID N A, PAYNE C D, SMALL D S, et al. Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently [ J ]. Clin Pharmacol Ther, 2007, 81 (5):735-741.
  • 2FDA. Label approved on 07/10/2009 for EFFIENT,NDA no. 022307 [EB/OL]. http: //www. accessdata. fda. gov/drugsatfda-docs/labelZ 2009/022307s0001bl. pdf.
  • 3JAKUBOWSKI J A, PAYNE C D, WEERAKKODY G J, et al. Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects[ J]. J Cardiovasc Pharmacol, 2007, 49 (3) : 167-173.
  • 4WALLENTIN L, VARENHORST C, JAMES S, et al. Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibi- tion than clopidogrel due to more effcient generation of its active metabolite in aspirin-treated patients with coronary artery disease [J]. Eur Heart J, 2008, 29(1):21-30.
  • 5WIVIOTT S D, BRAUNWALD E, MCCABE C H, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes[ J]. N Engl J Med, 2007, 357(20):2001-2015.

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