梅毒抗体血清学检测方法比较与评价

目的:比较梅毒血清学检测方法的特异性、敏感性,推荐目前临床实验室对梅毒性病的最佳检测方法。方法:本文采用TRUST、TP-ElisA、TPPA3种方法。结果:TP-ElisA法敏感性高、特异性强,适用于正在或曾经感染过梅毒的检测,适用于血站对献血员的筛选,但不适用于梅毒疗效观察;而TRUST敏感性低、特异性差,但适用于梅毒病人疗效观察。结论目前实验室的梅毒诊断采用TP-ElisA与TRUST组合最佳。

Objective：to compare to pick the specificity of detection serology method of syphilis, sensitivity, and recommend the clinical laboratory for syphilis venereal best detection methods. Methods： based TRUST and TP - ElisA,TPPA three methods. Results TP - ElisA, high sensitivity and specificity is applicable to the syphilis infection or used for testing, applicable to a blood donation of screening, but not for syphilis curative effects, Low sensitivity and specificity of TRUST and poor, but applies to syphilis patients. Conclusion using laboratory syphilis diagnosis with dogs - ElisA TP optimal combination.