口蹄疫病毒感染机理及防控策略的研究进展

Research Progress of Virus Infection Mechanism and Preventive Strategy of Foot-and-Mouth Disease

口蹄疫病毒(Foot-and-Mouth Disease Virus,FMDV)可导致牛、羊、猪等发生口蹄疫(Foot-and-mouth disease,FMD),该病毒有7种血清型,并具有高度变异性、适应性及持续感染特点,使得该病不能有效被控制而在许多国家和地区重新暴发和流行。论文对FMDV感染机理、口蹄疫难以防控的因素及目前常用的防制策略等方面进行了回顾,并对其研究前景进行了展望。

Foot-and-mouth disease （FMD） is a highly contagious disease of cloven-hoofed animals including cattle, swine and sheep, which is caused by Foot-and-Mouth Disease Virus （FMDV）. There are seven serotypes of FMDV, and variability, adaptability, and persistent infection of FMDV is the major reason that FMD is not easily controlled and it outbreaks and spreads in many countries and regions once again. This review summarizes the status of the FMDV infection mechanism, relevant factors for difficult control and commonly strategy to prevent FMD, and prospects development of them.