结直肠癌术后辅以放疗、化疗的临床观察

The clinical observation of colorectal carcinoma by post-operative radio-chemotherapy

目的探讨结直肠癌术后的有效辅助治疗,以积累临床经验,指导临床工作。方法选取我院诊治的320例患者,依随机的原则分为4组,A组共80例,术后不进行任何治疗;B组共80例,术后辅以放疗,C组共80例,术后辅以化疗,D组共80例,术后辅以放疗及化疗,观察各组的疗效及术后生存率。结果术后1年随访,生存率未见明显差别;术后2年随访,D组的生存率明显高于A、B、C组;术后5年随访,D组的生存率明显高于A、B、C组,B、C组的生存率明显高于A组。结论对结直肠癌患者术后应进行放、化疗,能明显提高临床疗效,临床中可以开展应用。

Objective To study the efffect of colorectal carcinoma by post-operative radio-chemotherapy,for accumulation clinical experience,directing clinical work. Methods 320 cases with colorectal carcinoma were divided into four groups（ A、B、C、D） . The A group included 80 cases,which were treated only by operation. The B group included 80 cases,which were treated by operation and radiotherapy. The C group included 80 cases,which were treated by operation and chemotherapy. The D group included 80 caese,which were treated by operation and radio-chemotherapy. The effect and survival rate were observed in four group. Results There were not obviously different in four group of 1 year. The survival rate were higher in the D group than in the A,B and C group of 2 year. The survival rate were higher in the D group than in the A,B and C group of five year. The survival rate were higher in the B and C group than A group of five year. Conclusion The post-operative radiochemotherapy is worthy of being recommended in colorectal carcinoma.