D-9二聚体对老年人骨科大手术后深静脉血栓的诊断价值

D-9dimer after major surgery on the elderly orthopedic diagnosis of deep vein thrombosis

目的探讨血浆D-9二聚体对老年人骨科大手术后发生深静脉血栓的临床价值。方法本组入选对象为我院2008年1月-2010年骨科住院患者60例,60例老年骨科手术根据是否深静脉血栓分为A组并发深静脉血栓22例、B组未并发深静脉血栓38例,采用酶联免疫吸附试验双抗体夹心法分别检测患者术前、术后第1天、第3天的血浆D-9二聚体的含量,并进行比较。结果两组术前血浆D-9二聚体含量比较差异无显著性,随着时间的增加,两组血浆D-9二聚体含量也呈渐进性增加,且术后第1天、术后第3天的血浆D-9二聚体含量两组间分别比较,差异有显著性。结论观察骨科老年人患者术后D-9二聚体的变化水平,对于了解是否并发深静脉血栓及病情变化和预后具有重要的临床意义。

Objective To evaluate plasma D-9dimer occurred after major surgery on the elderly orthopedic clinical value of deep vein thrombosis.Methods 60 elderly patients with orthopedic surgery,depending on whether deep venous thrombosis were divided into A group of 22 cases complicated with deep vein thrombosis,B group with no complication of deep vein thrombosis,38 cases using enzyme-linked immunosorbent assay double antibody sandwich method were detected preoperatively,postoperative day 1,day 3 of plasma D-9dimer levels,and compared.Results Preoperative plasma D-9dimer was no significant difference,as time increases,the two groups of plasma D-9dimer levels also showed gradual increase,and after 1 day after the operation 3 days of plasma D-9dimer levels were compared between the two groups,the difference was significant.Conclusion The observation of elderly orthopedic patients D-9dimer level,for to know if deep venous thrombosis and the disease stages and prognosis has important clinical significance.