摘要
目的:观察黄芪注射液联合重组人白细胞介素2对术后化疗后胃癌患者免疫功能的影响。方法:胃癌术后化疗后患者随机分为3组,分别给予黄芪注射液、重组人白细胞介素-2、黄芪注射液联合重组人白细胞介素-2,观测治疗前后患者症状、生存质量、T细胞亚群、NK数量等变化。结果:黄芪注射液可以缓解胃癌术后化疗后患者的症状,改善生存质量,提高受到抑制的CD3、CD4、CD8以及NK细胞的数量;IL-2可以提高胃癌术后化疗后患者CD3、CD8以及NK细胞的数量。黄芪注射液联合IL-2可以达到协同的作用。结论:黄芪注射液联合IL-2可以用于胃癌患者手术化疗后免疫功能低下的治疗。
Objective：To observed the effects of Huangqi Injection with Interleukin-2（ IL-2） on the immune function of gastric cancer patients. Methods：Gastric cancer patients who received surgery and chemotherapy were randomly divided into three groups,and treated with Huangqi Injection with IL-2 or Huangqi Injection or IL-2 alone. Results：Huangqi Injection could palliate the related symptom,and improve quality of life in gastric cancer patients who had received surgery and chemotherapy. In addition,CD 3＋ 、CD 4＋ 、CD 8＋ T cell and NK cell counts also elevated after Huangqi Injection therapy. Interleukin-2 can elevate CD 3＋ 、CD 8＋ T cell and NK cell counts in gastric cancer patients who had received surgery and chemotherapy. Huangqi Injection with Interleukin-2 could elicit synergistic effects to improve immune function. Conclusion：Huangqi Injection with Interleukin-2 can be used for improve immune function in gastric cancer patients who had received surgery and chemotherapy.
出处
《辽宁中医杂志》
CAS
北大核心
2010年第9期1733-1735,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
上海市科委攻关计划(064119625)
上海市浦东新区中医领军型人才项目(PWZ2008-20-104)
国家自然科学基金(30873258)
关键词
黄芪
白细胞介素-2
胃癌
免疫
astragalus membranaceus
interleukin-2
gastric cancer
immune
