27例支气管肺炎合并心力衰竭临床分析

27 cases of bronchial pneumonia complicated by heart failure

目的:研究支气管肺炎合并心力衰竭的发病机制。方法:回顾分析本科2009年4月～2010年3月符合支气管肺炎合并心力衰竭诊断的27例患者的临床资料,并与同期30名正常健康体检者的资料进行比较。结果:观察组和对照组射血分数(EF)、缩短分数(FS)比较差异无统计学意义(P>0.05);观察组血管紧张素Ⅱ(AngⅡ)浓度为(345±172)ng/L与正常对照组的(40±6)ng/L相比显著增高,差异有统计学意义(P<0.05);两组红细胞内游离钙比较,观察组红细胞内游离钙值为1.90±0.28,显著高于对照组的1.65±0.23,差异有统计学意义(P<0.05)。结论:支气管肺炎合并心力衰竭无心肌收缩力下降,但AⅡ的增加致心脏后负荷增加,可能在支气管肺炎合并心力衰竭的发病中起到重要作用。

Objective： Study of bronchial pneumonia complicated by heart failure pathogenesis. Methods： Review of course from April 2009 to March 2010 consistent with the diagnosis of bronchial pneumonia and heart failure clinical data of 27 patients and compared with 30 normal healthy patients to compare the data. Results： The observation group and con- trol group ejection fraction（EF）, fractional shortening（FS） and render not significant compared（P0.05）; observation group angiotensin Ⅱ（Ang Ⅱ） concentration（345±172） ng/L and normal control group（40±6） ng/L was significantly higher than, the difference was statistically significant （P0.05）; two red blood cell intracellular free calcium, to observe the group red blood cell intracellular free calcium value 1.90±0.28 was significantly higher than 1.65±0.23, the difference was significant （P0.05）. Conclusion： The bronchial pneumonia complicated by heart failure without myocardial contractility, but the A Ⅱ induced increase in cardiac afterload may increase the incidence of bronchial pneumonia complicated by heart failure plays an important role.