期刊文献+

大肠癌患者术前血清CRP水平测定及与临床病理特征和预后的关系 被引量:7

下载PDF
导出
摘要 目的探讨术前血清C-反应蛋白(CRP)水平在预测大肠癌患者预后中的作用。方法对82例大肠癌患者于切除术前检测CRP水平,分析后者与患者临床病理特征及预后的关系。结果术前血清CRP水平升高(>10 mg/L)与血清CRP正常(≤10 mg/L)者年龄及性别无显著差异,但并发症、肿瘤远处转移发生情况及Dukes分期有显著差异(P<0.05、0.05、0.01);术前血清CRP水平升高者总体生存期及无病生存期均显著短于血清CRP正常者(P<0.01、0.05)。结论大肠癌患者术前血清CRP水平与其并发症及肿瘤远处转移发生情况、Dukes分期、预后密切相关;其检测方法简单易行,利于临床常规筛查。
出处 《山东医药》 CAS 北大核心 2010年第35期49-50,共2页 Shandong Medical Journal
  • 相关文献

参考文献4

  • 1McMillan DC,Canna K,McArdle CS.Systemic inflammatory response predicts survival following curative resection of colorectal cancer[J].Br J Surg,2003,90(2):215-219.
  • 2Wang CS,Sun CF.C-reactive protein and malignancy:clinico-pathological association and therapeutic implication[J].Chang Gung Med J,2009,32(5):475-482.
  • 3Wong VKH,Malik HZ,Hamady ZZR,et al.C-reactive protein as a predictor of prognosis following curative resection for colorectal liver metastases[J].Br J Cancer,2007,96(2):222-225.
  • 4Gomez D,Morris-Stiff G,Wyatt J,et al.Surgical technique and systemic inflammation influences long-term disease-free survival following hepatic resection for colorectal metasis[J].J Surg Oncol,2008,98(5):371-376.

同被引文献41

  • 1黄国福,李迅,郭建琳,谌宏鸣.食管癌肿瘤标志物的研究进展[J].国外医学(临床生物化学与检验学分册),2004,25(6):532-535. 被引量:6
  • 2Ines Gockel,Kathrin Dirksen,Claudia M Messow,Theodor Junginger.Significance of preoperative C-reactive protein as a parameter of the perioperative course and long-term prognosis in squamous cell carcinoma and adenocarcinoma of the oesophagus[J].World Journal of Gastroenterology,2006,12(23):3746-3750. 被引量:12
  • 3Yingqiu Song Guiling Li Fang Zhu Fangzheng Zhou Sheng Zhang Jing Wang Zhongyuan Ying.Clinical study of paclitaxel plus cisplatin in the treatment of recurrent cervical cancer[J].The Chinese-German Journal of Clinical Oncology,2007,6(3):282-284. 被引量:9
  • 4Wang CS,Sun CF.C-reactive protein and malignancy:clinico-pathological association and therapeutic implication[J].Chang Gung Med J,2009,32(5):471-482.
  • 5Shacter E,Weitzman SA.Chronic inflammation and cancer[J].Oncology {Williston Park),2002,16(2):217-226,229;discussion 230-232.
  • 6Milasiene V,Stratilatovas E,Norkiene V,et al.Lymphocyte subsets in peripheral blood as prognostic factors in colorectal oancer[J].J BUON,2005,10(2):261-264.
  • 7Fogar P,Sperti C,Basso D,et al.Decreased total lymphocyte counts in pancreatic cancer:an index of adverse outcome[J].Pancreas,2006,32(1):22-28.
  • 8Oh BS,Jang JW,Kwon JH,et al.Prognostic value of C-reactive protein and neutrophil-to-lymphocyte ratio in patients with hepatocellular carcinoma[J].BMC Cancer,2013,13:78-86.
  • 9La Torre M,Nigri G,Cavallini M,et al.The glasgow prognostic score as a predictor of survival in patients with potentially resectable pancreatic adenocarcinoma[J].Ann Surg Oncol,2012,19(9):2917-2923.
  • 10Ikuta Y,Takamori H,Sakamoto Y,et al.The modified Glasgow Prognostic Score(mGPS)is a good predictor of indication for palliative bypass surgery in patients with unresectable pancreatic and biliary cancers[J].Int J Clin Oncol,2014,19(4}:629-633.

引证文献7

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部