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老年心肌梗死患者血清肺炎衣原体IgG、ET-1、IL-6、sVCAM-1、hsCRP水平测定及分析 被引量:7

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摘要 目的探讨肺炎衣原体感染在老年人急性心肌梗死发病中的作用及可能机制。方法研究对象为20例老年急性心肌梗死患者(观察组)与20例健康体检者(对照组),采用ELISA法检测其血清中肺炎衣原体IgG、内皮素-1(ET-1)、IL-6、可溶性血管细胞黏附分子-1(sVCAM-1)、高敏C-反应蛋白(hsCRP)水平。结果观察组血清肺炎衣原体IgG阳性8例、抗体浓度为67.55±52.80,对照组分别为2例和18.75±14.33,组间比较P均<0.05;观察组血清ET-1为(51.26±25.31)pg/ml、IL-6为(63.07±95.26)pg/ml、sVCAM-1为(27.04±26.66)nmol/L、hsCRP为(24.82±30.16)mg/L,对照组分别为(31.19±10.24)pg/ml、(25.21±18.33)pg/ml、(6.13±5.57)nmol/L、(3.15±2.39)mg/L,组间比较P均<0.05。结论肺炎衣原体感染在老年急性心肌梗死发病中发挥一定作用,机制可能与上调ET-1、IL-6、sVCAM、hsCRP等炎性标志物活性有关。
作者 唐维敏
出处 《山东医药》 CAS 北大核心 2010年第35期54-55,共2页 Shandong Medical Journal
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