早发型重度子痫前期28例临床分析

The clinical analysis to 28 cases of early onset severe pre-eclampsia

目的：探讨早发型重度子痫前期临床特点、保守治疗时间及妊娠结局。方法：回顾分析西安市红十字会医院妇产科2006年12月—2009年12月收治的28例早发型重度子痫前期（≤32周）患者的临床资料,分别记录不同保守治疗时间及其严重并发症发生情况、胎儿及新生儿情况。将所有患者分为3组,A组10例,治疗时间≤48 h;B组10例,治疗时间为7~10 d;C组8例,治疗时间≥14 d。结果：B组妊娠结局明显优于A组及C组,差异有统计学意义（P〈0.05）。并发症发生率依次为胎盘早剥、肾衰竭、子痫。结论：早发型重度子痫前期,保守治疗需严密监测,适时终止妊娠,降低母儿病率及死亡率。

Objective：To investigate clinical traits,the period of conservative management and pregnancy outcome in early onset severe pre-eclampsia.Methods：To analyse the clinical data of 28 cases of early onset severe pre-eclampsia（less than 32 weeks） in this study.The period of conservatire management,complication and the situation of fetus and infant were retrospectively recorded in serials.All patients were divided into three groups,the period of conservative management less than 48 h（group A）;That of was 7～10 days（group B） and more than 14 days（group C）.Results：Maternal and perinatal outcomes in group B were well than which of group A and group C（P0.01）.The commonest maternal complications was placental abruption,then were renal function failure and eclampsia.Conclusion：Expectant management should be carried out in well selected patients with early onset severe pre-eclampsia,pregnancy might be terminated in due time after a proper period of expectant management to decline the perinatal morbidity and mortality.