66例IgA肾病的随访设计及其临床意义

The clinical efficacy of survey for IgA nephropathy of 66 cases

目的:观察专业性的随访对于IgA肾病患者的临床疗效。方法:将66例IgA肾病患者随机分为随访组33例,对照组33例。随访组按设定的随访项目做出院指导,并从心理疏导治疗、定期门诊检查、预约住院综合治疗等三个方面进行干预;对照组则仅做出院指导。随访时间均为1年。结果:以睡眠改善程度和心理健康状态、蛋白尿或血尿波动程度等方面综合评价,随访组均明显低于对照组,差异有统计学意义(P<0.01或P<0.05)。结论:定期随访对于IgA肾病患者而言具有重要的临床意义,它能明显改善患者睡眠质量,减轻患者焦虑和抑郁症状,有利于稳定蛋白尿、血尿,延缓肾功能不全进展速度。

Objective ： To observe the effect of survey for IgA nephropathy patients. Methods ：66 cases of IgA nephropathy patients were randomly divided into two groups ： 33 cases of follow - up group and 33 cases of control group. PatientS in follow - up group underwent psychotherapy,regularly outpatient exami- nation, reservation for being treated compositly in hospital, such three aspects to be continued ,and patients in control group had no the treatment above. Re- sults ：The evaluation of improvement of sleepling quality （PSQI factor score） and mental health status （SAS factor score） proteinuria or hematuria fluctuation, the follow - up group was significantly slower than that in control group, the difference have statistics significance（ P 〈 0. 01 ,P 〈 0.05）. Conclusion ： The regularly follow -up for IgA nephropathy patients had the important clinical effect, its can improve sleep quality of IgA nephropathy patients and reduce anxiety symptoms,and stabilize proteinuria or hematuria,so as to retard the progress of Chronic renal failure.