肾移植受者术后早期神经系统并发症

Neurological Complications in Early Post-operation of Renal Transplant Recipients

目的探讨肾移植术后早期神经系统并发症的类型、发生率及危险因素。方法总结3169例次肾移植受者的术后临床过程,对102例住院期间出现神经系统并发症的临床资料进行回顾性分析。结果神经系统并发症的总发生率3.2%;其中脑病35例(1.1%),癫痫发作24例(0.76%),急性脑卒中15例(0.47%),周围神经病变15例(0.47%),头痛12例(0.38%),中枢神经系统感染1例(0.03%)。结论肾移植术后早期神经系统并发症多样,以脑病及癫痫发作较为常见。推测某些并发症可能与应用免疫抑制剂有一定关系。

Objective To investigate the incidence,types and risk factors of neurological complications in the early post-operation of renal transplantation.MethodsThe clinical course of 3169 cases of renal transplantation were reviewed,the clinical data of 102 patients with neurological complications were analyzed retrospectively.ResultsThe total incidence of neurological complications was 3.2%,which including：encephalopathy 35（1.1%）,seizure 24（0.76%）,acute stroke 15（0.47%）,peripheral nerve disease 15（0.47%）,headache 12（0.38%）,central nervous system infection 1（0.03%）.ConclusionThere were varied of neurological complications of renal transplantation in early post-operation,in which encephalopathy and seizure were more common.Some of the complications may be related to immunosuppressive agents.