摘要
硫酸胍基丁胺是一种极具开发价值的戒毒类药物,市场运用前景广阔。本文以1,4-二溴丁烷与邻苯二甲酰亚胺钾为原料,经取代、胺解和胍基化等三步反应制得硫酸胍基丁胺,总收率为33.9%,产品含量99.5%。
Agmatine sulfate is a detoxification drug with great development value and broad market foreground.It was synthesized with 33.9% overall yield and content of 99.5% by three-step reactions through substitution,aminolysis and Guanidine reaction from the starting materials: 1,4-butylenedibromide and phthalimide potassium.
出处
《浙江化工》
CAS
2010年第9期5-7,共3页
Zhejiang Chemical Industry
基金
浙江省科技计划资助项目(2008C21038)