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硫酸胍基丁胺的绿色合成工艺研究 被引量:3

Green Process for the Preparation of Agmatine Sulfate
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摘要 硫酸胍基丁胺是一种极具开发价值的戒毒类药物,市场运用前景广阔。本文以1,4-二溴丁烷与邻苯二甲酰亚胺钾为原料,经取代、胺解和胍基化等三步反应制得硫酸胍基丁胺,总收率为33.9%,产品含量99.5%。 Agmatine sulfate is a detoxification drug with great development value and broad market foreground.It was synthesized with 33.9% overall yield and content of 99.5% by three-step reactions through substitution,aminolysis and Guanidine reaction from the starting materials: 1,4-butylenedibromide and phthalimide potassium.
出处 《浙江化工》 CAS 2010年第9期5-7,共3页 Zhejiang Chemical Industry
基金 浙江省科技计划资助项目(2008C21038)
关键词 硫酸胍基丁胺 1 4-丁二胺 O-甲基异脲硫酸盐 agmatine sulfate 1 4-butanediamine O-methylisourea hemisulfate
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参考文献9

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