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普拉克索治疗不宁腿综合征临床研究 被引量：1

Clinical study on pramipexole in treating restless legs syndrome
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摘要 目的:观察普拉克索对不宁腿综合征(RLS)的治疗效果。方法:对41例不宁腿综合征患者随机分为两组,对照组20例予以氯硝基安定、维生素B1、弥可保口服;治疗组21例在对照组基础上加用普拉克索睡前口服治疗,疗程4周。结果:对照组总有效率65.0%,治疗组总有效率90.5%,两组比较有统计学差异(P<0.01)。结论:普拉克索治疗有效,无明显副作用,值得临床推广。 Objective：To oberserve the therapeutic result of pramipexole in treating restless legs syndrome （RLS）.Methords：The 41 cases of restless legs syndrome were randomly divided into two groups.The 20 patients in control group were treated with chlorine nitrazepam,vitamin B1,methylcobalamin for 4 weeks.The 21 cases in treatment group were treated with pramipexole in additional On the basis of the control group for 4 weeks at bedtime.Results：The total efficiency in control group is 65.0%,but the efficiency in treatment group is 90.5%.There were statistics differences between the two groups（P0.01）.Conclusion：the drug of pramipexole is effective to treat restless legs syndrome.It was no side effects,and worthy of promotion.
作者 肖兵 王蕾 徐朝义 高励
机构地区 成都市第三人民医院神经内科
出处 《医学信息（中旬刊）》 2010年第9期2306-2307,共2页 Medical Information Operations Sciences Fascicule
关键词 不宁腿综合征 普拉克索 药物治疗 Restless legs syndrome Pramipexole Drug therapy
分类号 R747.8 [医药卫生—神经病学与精神病学]
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参考文献6

  • 1孟昭义,王维治,主编.不安腿综合征[M].神经病学.北京:人民卫生出版社,2006:258-261.
  • 2Allen RP,Picchietti D,Hening WA,et al.Restless legs syndrome:diagnostic criteria,special considerations,and epidemiology.A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health[J].Sleep Med,2003,4:101-119.
  • 3Clardy SL,Early CJ,Aclen RP,et al.Ferritin Subun its in CSF de screased in restless legs[J].Syndrome J lab clinned,2006,147(2):67-83.
  • 4Hening WA.Current guidelines and standards of practice for restless legs syndrome[J].Am J Med,2007,120(1A):S22-S27.
  • 5赵红如,乐卫东.多巴胺与不安腿综合征[J].中国新药与临床杂志,2006,25(3):211-215. 被引量：16
  • 6Kushida CA.Pramipexole for the treatment of restless legs syndrome.Expert Opin Pharmacother,2006,7(4):441-451.

二级参考文献25

  • 1ROTHDACH AJ,TRENKWALDER C,HABERSTOCK,et al.Prevalence and risk factors of RLS in an elderly population:the MEMO study.Memory and Morbidity in Augsburg Elderly[J].Neurology,2000,54(5):1064-1068.
  • 2ULFBERG J,NYSTROM B,CARTER N,et al.Restless legs syndrome among working-aged women[J].Eur Neurol,2001,46 (1):17-19.
  • 3ABRAHAMSON EE,MOORE RY.Suprachiasmatic nucleus in the mouse:retinal innervation,intrinsic organization and efferent proje ctions[J].Brain Res,2001,916(1-2):172-191.
  • 4CHESSON AL,WISE M,DAVILA D,et al.Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder[J].Sleep,1999,22 (7):961-968.
  • 5HENING W,ALLEN R,EARLEY C,et al.The treatment of restless legs syndrome and periodic limb movement disorder[J].Sleep,1999,22 (7):970-999.
  • 6TURJANSKI N,LEES AJ,BROOKS DJ.Striatal dopaminergic function in restless legs syndrome:18F-dopa and 11C-raclopride PET studies[J].Neurology,1999,52(5):932-937.
  • 7MICHAUD M,SOUCY JP,CHABLI A,et al.SPECT imaging of striatal pre and postsynaptic dopaminergic status in restless legs syndrome with periodic leg movements in sleep[J].J Neurol,2002,249(2):164-170.
  • 8QU S,ONDO WG,ZHANG X,et al.Projections of diencephalic dopamine neurons into the spinal cord in mice[J].Exp Brain Res,2005:1-5.
  • 9ONDO WG,HE Y,RAJASEKARAN S,et al.Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats:a possible model for restless legs syndrome?[J].Mov Disord,2000,15(1):154-158.
  • 10CLEMENS S,HOCHMAN S.Conversion of the modulatory actions of dopamine on spinal reflexes from depression to facilitation in D3 receptor knock-out mice[J].Neurosci,2004,24 (50):11337-11345.

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医学信息（中旬刊）
2010年 第9期

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