摘要
目的:探讨奥氮平与奎的治疗精神分裂症的疗效和安全性。方法:将34例精神分裂症患者随机分为观察组(用奥氧平治疗)与对照组(用奎的平治疗)种17例。治疗期间观察组脱落1例,实际完成16例,对照组脱落1例,实际完成16例。两组疗程均为8周。于治疗前及治疗第2、4、8周末采用阳性与阴性症状量表评定临床疗效,副反应量表评定不良反应,并进行对比分析。结果:观察组显效率68.9%,有效率94.0%;对照组显效率70.8%,有效率93.5%,两组间比较我均无显著性差异(p>0.05)。观察组不良反应比对照组少且轻。结论:奥氮平治精神分裂疗效确切,不良反应少,服药依从性好。
Objective：To explore the curative effect and safety of olanzapine vs quetiapine in the treatment of schizophrenia.Methods：68 schizophrenic patients were randomly divided into research？ Group （tookf olanzapin,n 17）and control group,1 quitted and 16 completed in the control group.The therapeutic effectiveness and side effects were assessed with the positive And Negative symptom Scale（PANSS）and Treatment Emergent Symptom Scale（TESS）before treatment and at the ends of 2nd,4thand 8th week of treatment,respectively.Results：Effectual and effective rates of the research group were 68.9% and 94.0% and those of the control group 70.9% and 93.5% respectively,which had no significant difference （P0.05）.The side effects in olanzapine group were fewer and mider.Conclusion：Olanzapine has reliable effectiveness,fewer side effects and better compliance in the treatment of schizophrenia.
出处
《医学信息（中旬刊）》
2010年第9期2325-2326,共2页
Medical Information Operations Sciences Fascicule
