丹参与神经节苷脂联合治疗新生儿缺氧缺血性脑病疗效观察

Observation in therapeutic effect of salvia miltiorrhiza and ganglioside on neonatal hypoxic-ischemic encephalopathy

目的:观察丹参与神经节苷脂联合治疗新生儿缺氧缺血性脑病的临床疗效。方法:将105例新生儿缺氧缺血性脑病患儿随机分为2组,治疗组用丹参与神经节苷脂联合治疗;对照组用胞二磷胆碱。结果:两组患儿临床疗效比较,治疗组明显高于对照组(p<0.05)。结论:联合用药治疗新生儿缺氧缺血性脑病有协同作用,能改善脑缺血区血流灌注,促进神经细胞代谢,减少神经系统后遗症,疗效肯定。

Objective：The aim of the study is to observe the clinical effects of salvia miltiorrhiza and ganglioside on neonatal hypoxic-ischemic encephalopathy.Methods：105 cases with hypoxic-ischemic encephalopathy is divided into test group and control group by random.The control group is treated by nicholin,the test group is treated by salvia miltiorrhiza and ganglioside,then observe their clinical efficiency.Results：Comparison of clinical effect in two group,the test group is significantly higher than control group（P0.05）.Conclusion：The treatment with danshen and ganglioside on neonatal hypoxic-ischemic encephalopathy has synergistic effect.It can improve blood flow in cerebral ischemic reperfusion,promote nerve cell metabolism,reduce nervous system sequela.