针灸对干眼症泪液分泌影响的疗效评价

Efficacy assessment of acupuncture and moxibustion on tear secretion in xerophthalmia

目的:对比针灸与药物治疗干眼症的疗效差异。方法:将80例干眼症患者随机分为针灸组和药物组,每组40例。针灸组采用针刺局部和远端相结合的方法,穴取睛明、攒竹、太阳、曲池等,配合无烟灸温灸;药物组采用玻璃酸钠滴眼液滴眼,每日3次,每次1滴。观察治疗前后患者泪液分泌量(Schirmer法)、泪膜破裂时间(BUT)、症状评分、视功能评分及泪液镜分级变化。结果:针灸组总有效率为73.1%(57/78),药物组为37.2%(29/78),差异有统计学意义(P<0.05)。治疗后两组泪液分泌量比较,差异有统计学意义(P<0.05),针灸组优于药物组。针灸组治疗前后泪液分泌量、BUT、症状评分、视功能评分及泪液镜分级比较,差异均有统计学意义(均P<0.05);药物组治疗前后仅症状评分、泪液镜分级比较差异有统计学意义(均P<0.05)。结论:针灸治疗可以明显改善干眼症状,促进泪液分泌,提高患者生活质量。

Objective To compare the efficacy differences between acupuncture-moxibustion and medication in xerophthalmia. Methods Eighty cases of xerophthalmia were randomly divided into an acupuncture-moxibustion group and a medication group, 40 cases in each group. In acupuneture-moxibustion group, acupuncture was applied to the local and distal points, such as Jingming （BL 1）, Cuanzhu （BL 2）, Taiyang （EX-HN 5） and Quchi （LI 11） etc. , combined with non-smoking moxibustion. In medication group, Sodium Hyaluronate eye drops were administered, three times per day, 1 drop each time. Before and after treatment, tear secretion volume （Schirmer＇s test）, break-up time （BUT）, symptom score, visual function score and tear film grade were observed. Results The total effective rate was 73. 10% （57/78） in acupuncture-moxibustion group, and was 37. 2% （29/78） in medication group, indicating significant statistical difference in comparison （P〈0.05）. There was a significant difference in statistics in tear secretion volume between two groups after treatment （P〈0. 05）, in which, the result in acupuncture-moxibustion group was superior to that in medication group. The significant statistical differences presented in tear secre- tion volume, BUT, symptom score, visual function score and tear film grade in comparison before and after treatment in acupuncture-moxibustion group （all P〈0. 05）. The significant statistical difference presented in symptom score and tear film grade before and after treatment in medication group （both P〈0. 05）. Conclusion Acupuncturemoxibustion apparently relieves the symptoms of xerophthalmia, promotes tear secretion and improves the life quality of patients.