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老年原发性高血压伴2型糖尿病肾损害微量白蛋白尿期内皮细胞功能变化 被引量：5

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摘要 有学者认为高血压病和糖尿病是同源性疾病，可能存在共同的遗传基因，共同的始动因素。两种疾病并存在老年人群中逐年增高，带来继发性肾损害增多。高血压和糖尿病可使内皮细胞功能的发生变化，我们通过检测老年原发性高血压（3级）和（或）2型糖尿病患者的内皮细胞功能，旨在探讨原发性高血压伴2型糖尿病肾损害微量白蛋白尿期内皮细胞功能变化，为临床治疗提供依据。
作者 王秋雁 毕丽珠 章昕
机构地区 杭州市中医院重症监护室
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2010年第8期671-673,共3页 Chinese Journal of Geriatrics
关键词 2型糖尿病肾损害 老年原发性高血压 内皮细胞功能 细胞功能变化 蛋白尿期 继发性肾损害 高血压病 遗传基因
分类号 R544.1 [医药卫生—心血管疾病]
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  • 1Adler SG, Pahl M, Seldin MF.Deciphering diabetic nephropathy: progress using genetic strategies.Curr Opin Nephrol Hypertens,2000,9:99-106.
  • 2Lansang MC, Hollenberg NK.Renal perfusion and the renal hemodynamic response to blocking the renin system in diabetes: are the forces leading to vasodilation and vasoconstriction linked?Diabetes,2002,51:2025-2028.
  • 3Volker V, Roland CB, Scott T, et al. Glomerular hyperfiltration and the salt paradox in rarly type 1 diabetes mellitus: a tubulo-centric view. J Am Soc Nephrol, 2003,14:530-537.
  • 4Sheetz MJ, King GL.Molecular understanding of hyperglycemia's adverse effects for diabetic complications.JAMA,2002,288:2579-2588.
  • 5Brownlee M. Biochemistry and molecular cell biology of diabetic complications.Nature,2001,414:813-820.
  • 6Forbes JM, Cooper ME, Thallas V, et al. Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy.Diabetes,2002,51:3274-3282.
  • 7Evans JL, Goldfine ID, Maddux BA,et al. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev, 2002,23:599-622.
  • 8White KE, Bilous RW, Marshall SM, et al. Podocyte number in normotensive type 1 diabetic patients with albuminuria.Diabetes,2002,51:3083-3089.
  • 9Batlle D. Clinical and cellular markers of diabetic nephropathy.Kidney Int,2003,63:2319-2330.
  • 10Kveder R, Kajtna-Koselj M, Rott T, et al. Nephrotic syndrome in patients with diabetes mellitus is not always associated with diabetic nephropathy.Nephrol Dial Transplant,2001,16 Suppl 6:86-87.

共引文献146

同被引文献50

  • 1阮雪玲,张秀薇,郑东文,佘燕萍,吴恒莲,刘国辉,林宏初.黄芪和丹参注射液联用对早期糖尿病肾病血液流变学和肾功能的影响[J].中国实用内科杂志,2005,25(2):147-149. 被引量：79
  • 2于世鹏,班博,孙琳,赵秀贞,孙海玲,张梅,李萍.糖尿病高血压对大血管并发症的影响[J].中国实用内科杂志,2005,25(11):1033-1034. 被引量：8
  • 3苏庆军,王一男,陈建国,唐茂林.纤维蛋白原的临床意义及测定[J].实用医技杂志,2006,13(23):4273-4274. 被引量：27
  • 4Onuigbo M,Weir MR. Evidence-based treatment of hyper- tension in patients with diabetes mellitus [J]. Diabetes Obes Metab, 2003,5 ( 1 ) : 13-26.
  • 5Laakso M. Hyperglycemia as a risk factor for cardiovas- cular disease in type 2 diabetes [J]. Prim Care, 1999,26 (4) : 829-839.
  • 6Adler AI,Stratton IM,Neil HA,et al. Association of sys- tolic blood pressure with macrovascular and microvascular complications of type 2 diabetes(UKPDS 36) :prospective observational study[J]. BMJ, 2000,321(7258) :4t2-419.
  • 7Fang J,Alderman MH. Serum uric acid and cardiovascu- lar mortality the NHANESI epidemiologic follow-up study, 1971-1992. National health and nutrition examina- tion survey [ J ]. JAMA, 2002,283 (18) : 2404-2410.
  • 8Dobiasovd M,Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index., correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma[FER (HDL)]. Clin Biochem, 2001,34 : 383-386.
  • 9Himeh GA,Blumenthal RS. Usefulness of non-high- density lipoprotein cholesterol determinations in the diagnosis and treatment of dyslipidemia. Am J Cardiol, 2003, 91 ..827-830.
  • 10Mogensen CE. The natural history of diabetic nephropathy in insulinodependent diabetics and the concept of non-glycemic treatment. Journ Annu Diabetol Hotel Dieu, 1989, 225-246.

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中华老年医学杂志
2010年 第8期

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