冠心病并发焦虑症的临床治疗分析

Analysis of clinical treatment of coronary heart disease and anxiety disorders

目的:研究冠心病并发焦虑症患者同时接受小剂量抗焦虑药物治疗对冠心病治疗的影响。方法:40例冠心病并发焦虑症患者随机分成试药组和常规组,试药组在常规组基础上加用小剂量抗焦虑药物治疗,用药4周后分别比较临床心绞痛发作次数,心电图改善程度,以及焦虑症状评定。结果:两组患者同等劳动程度心绞痛发作次数均明显减少,试药组总有效率为96%,常规组总有效率为79%,差异有显著性(P<0.05)。两组心电图总有效率(试药组84%,常规组85%)比较差异无统计学意义,两组治疗后SAS分数均有下降,但常规组差异无统计学意义,试药组SAS分数显著下降(P<0.05),差异有统计学意义,评分亦明显低于常规组(P<0.05),提示试药组的焦虑症状较常规组明显改善。结论:加用小剂量抗焦虑药物,在同等劳动程度下心绞痛发作次数明显减少,患者的焦虑症状也得到有效改善。

AIM： To explore the effect of low-dose anti-anxiety medication in the treatment of coronary heart disease （CHD） in patients with both CHD and anxiety disorders. METHODS： Forty cases of CHD and anxiety disorder were randomly divided into treatment group and conventional group. In addition to the conventional treatment, patients in the treatment group were given low-dose anti-anxiety medication. Four weeks after treatment, the occurrence of angina pectoris, ECG improvement and anxiety symptom assessment were compared between groups. RESULTS： Under the same workload, the occurrence of angina pectoris was significantly reduced in both groups and the total effective rate in the treatment group was 96%, whereas that in the conventional group was 79%, with significant difference between groups （P 〈 0. 05 ）. No significant difference was observed in the effective rate of ECG between groups （ treatment group 84% vs. conventional group 85% ）. After treatment, SAS scores in both groups declined, but significant differences were only found in the treatment group （ P 〈 0. 05 ）. The SAS scores in the treatment group were significantly lower than in the conventional that anxiety symptoms in the treatment group were significantly more group （ P 〈 0. 05 ）, demonstrating improved in the treatment group. CONCLUSION： Low-dose anti-anxiety drugs significantly reduce the occurrence of angina pectoris, effectively alleviate anxiety symptoms and improve the quality of life in patients with both CHD and anxiety disorders.