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α1A/C-肾上腺素受体对心肌的保护作用

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摘要 心肌细胞上存在α1A/C、α1B、α1D,β1、β2、β3等肾上腺素受体(AR)亚型,均属于G蛋白偶联受体超家族。一般认为,β1等AR持续兴奋对心肌是有害的;而近来的研究发现,α1A/C-AR在压力超负荷和心肌梗死等病理情况下,可能对心肌具有保护作用。本文综述了α1A/C-AR对心脏功能的调节作用。
作者 牟杨 李刚 张灿晶
机构地区 重庆医科大学附属第一医院老年科心血管病组 重庆市西郊医院功能检查科
出处 《心脏杂志》 CAS 2010年第5期774-776,共3页 Chinese Heart Journal
基金 重庆市科委自然科学基金计划资助项目[渝科发计字(2007)25号CSTC 2007BB5276] 重庆市卫生局医学科学技术研究项目[渝卫教2004(53)04-2-154]
关键词 肾上腺素受体 α1A/C受体 心肌细胞
分类号 Q577 [生物学—生物化学]
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参考文献14

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二级参考文献9

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心脏杂志
2010年 第5期

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