摘要
目的探讨中药"四藤一仙汤"在糖尿病周围神经病变治疗中的作用和临床疗效。方法将147例糖尿病周围神经病变患者随机分为治疗组(74例)和对照组(73例),两组同时给予常规综合治疗,治疗组再给予中药"四藤一仙汤"口服,对照组再给予维生素B1100 mg和维生素B12250μg,肌肉注射。治疗2个月,对比两组患者治疗前后临床症状及神经传导速度的变化。结果两组患者治疗前正中神经、腓总神经的运动传导速度(MCV)和感觉传导速度(SCV)比较,差异均无统计学意义(P>0.05);治疗后正中神经、腓总神经的MCV和SCV比较,差异均有统计学意义(P<0.01)。结论中药"四藤一仙汤"养血活血、通络止痛,治疗糖尿病周围神经病变效果显著。
Objective To explore the clinical effect of Traditional Chinese Medicine（TCM） ＂Sitengyixiantang＂ on diabetic perineuropathy（DPN）.Methods A total of 147 DPN patients were divided randomly into groups therapy（n=74） and control（n=73）.Both were treated conventionally,but therapy group with additional TCM ＂Sitengyixiantang＂,orally,control group with intramuscular injection of vitamin B 1100 mg and vitamin B 12 250 μg.The treatment lasted 2 months.The changes of clinical symptoms and nerve conduction velocity were compared between 2 groups before and after treatment.Results There was not significant difference in median nerve,common peroneal nerve motor conduction velocity（MCV） and sensory conduction velocity（SCV） between 2 groups before treatment（P0.05）,but there was after treatment（P0.01）.Conclusion TCM ＂Sitengyixiantang＂,nourishing blood and promoting blood circulation,activating meridians to stop pain,has obvious effect on DPN.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第24期2766-2767,共2页
Chinese General Practice
关键词
糖尿病神经病变
中草药
综合疗法
Diabetic peripheral neuropathy（DPN）
Traditional chinese medicine（TCM）
Combined therapy
