口服胃窗声学造影剂超声检查对胃部病变的诊断价值

Clinical Application of Oral Ultrasonic Contrast Agent Ultrasonography in Differential Diagnosis of Gastric Lesions

目的探讨口服胃窗声学造影剂超声检查在胃部病变诊断与鉴别诊断中的应用价值。方法 68例获得病理确诊的胃部病变患者均进行了常规超声检查、口服胃窗声学造影剂超声检查及增强CT/MRI检查,以病理为金标准,评估口服胃窗声学造影剂超声检查对胃部病变的诊断价值。结果口服胃窗声学造影剂超声检查对68例胃部病变的显示率明显高于常规超声(95.6%vs17.6%,P<0.001)。以病理为金标准,常规超声对胃部病变诊断的准确性为13.2%,口服胃窗声学造影剂超声检查对胃部病变诊断的准确性为88.2%,增强CT/MRI对胃部病变诊断的准确性为89.7%。三种检查方法对胃部病变诊断的准确性两两比较,常规超声与口服胃窗声学造影剂超声检查相比,两者差异有统计学意义(P<0.001);口服胃窗声学造影剂超声检查与增强CT/MR相比,两者差异无统计学意义(P>0.05)。结论口服胃窗声学造影剂能消除胃内气体、黏液的干扰,明显提高对胃部病变的显示率及诊断的准确性,此方法操作简便、安全、无辐射,在临床上有广泛的应用价值。

Objective To evaluate the value of oral ultrasonic contrast agent ultrasonography（OUCAU） in differential diagnosis of gastric lesions.Methods The conventional ultrasonography（CU）,OUCAU,and CT/MR were performed in 68 patients with gastric lesions（confirmed by pathology）.According to pathologic findings,the value of OUCAU in differential diagnosis of gastric lesions was analyzed.Results The detection rate of OUCAU was higher than CU（95.6% Vs 17.6%,P0.001）.The diagnosis accuracy of CU,OUCAU,and CT/MR was 13.2%,88.2%,89.7%,respectively.There was a significant difference in diagnosis accuracy between CU and OUCAU（P0.001）.There was no significant difference in diagnosis accuracy between OUCAU and CT/MR（P0.05）.Conclusion OUCA can effectively eliminate interference of gastrointestinal contents and gas,and obviously improve the visualization and diagnosis accuracy.This method,without radioactivity,is easy and safe,and can be used widely in the clinic.