地方性砷中毒皮肤病调查报告

Investigative Report of Endemic Arsenic Toxic Dermatoses.

目的了解砷中毒皮肤病地域流行状况及主要临床表现。方法对高发地区水源进行砷含量测定，调查高发地区人群皮肤损害表现。结果调查１１２４例中，皮肤受累２６５例（２７．０７％）。主要表现为色素脱失、色素沉着及掌跖过度角化，具此三联症者７２例（７．３５％）。结论砷性皮肤改变主要发生在长期高坤环境下生活的居民中，主要临床表现为脱色、着色和过度角化。

Objective To investigate the endemic situation of arsenic toxic dermatoses and its main clinical manifestation.Method The arsenic concentration in water source was measured,and clinical appearence of skin involved lesions were determined inhigh incidence regions.Result The skin was involved in 265 cases (27.07%) out of investigated 1124 cases.The main manifestation was hypopigment,hyperpigment,and palmoplantar Hyperkeratosis.Triad cases happened in 72 patients (7.35%).Conclusion The arsenic toxic dermatoses can mainly be seen in residents who live in high arsenic areas for long time.The main clinical manifestation is hypopigment,hyperpigment and overkeratosis.