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胰岛素抵抗与慢性肾脏病的研究进展 被引量：1

Insulin Resistance and Chronic Kidney Disease
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摘要 在慢性肾脏病患者中,瘦素、脂联素、抵抗素和甲状旁腺功能亢进等多种因素在胰岛素抵抗和高胰岛素血症的发生和发展中起重要作用。随着胰岛素抵抗的出现,肾功能即出现损害的趋势,表现为在胰岛素受体前水平、受体水平和受体后水平均存在胰岛素抵抗,使胰岛素分泌、利用和灭活等均表现异常。 Various factors such as leptin,adiponectin,resistin and hyperparathyroidism play an important role in the development of insulin resistance and hyperinsulinemia in patients with chronic kidney disease.Upon the emergence of insulin resistance,renal function begins to decline,manifesting as pre-receptor,receptor and post-receptor IR and the abnormality in secretion,utilization and inactivation of insulin.
作者 陆晨 姬佳妮 岳华
机构地区 新疆维吾尔自治区人民医院肾病科
出处 《医学综述》 2010年第18期2729-2732,共4页 Medical Recapitulate
基金 科技部科技支疆项目(200840102-38)
关键词 胰岛素抵抗 慢性肾脏病 高胰岛素血症 Insulin resistance Chronic kidney disease Hyperinsulinemia
分类号 R692 [医药卫生—泌尿科学]
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参考文献24

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二级参考文献13

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共引文献31

同被引文献26

  • 1吴光驰.中国人群维生素D营养状况[J].中国妇幼卫生杂志,2010,1(1):51-54. 被引量：49
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  • 4陈晓蕾,宋滇平.C肽作用与糖尿病及其慢性并发症[J].中日友好医院学报,2007,21(3):175-177. 被引量：3
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医学综述
2010年 第18期

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