摘要
多囊卵巢综合征是妇科内分泌疾病,临床表现为排卵障碍及高雄激素血症,病因不明。高水平的雄激素抑制了下丘脑对黄体酮的敏感性,使其对促性腺素释放激素波动起始器的抑制作用减弱,促性腺素释放激素和黄体酮分泌异常,卵泡形成受损。促性腺素分泌异常、胰岛素抵抗、青春期神经内分泌异常都可能引起神经内分泌紊乱,导致多囊卵巢综合征的发生。
Polycystic ovary syndrome(PCOS)is a gynecological endocrine disease,which clinically manifests mainly as excessive androgen secretion,insulin resistance and infertility.Patients usually have hirsutism,acne,infertility,amenorrhea,and obesity.Teenage patients usually have oligomenorrhea or amenorrhea,hirsutism acne and overweight Women of child-bearing potential are usually infertile,in addition to oligomenorrhea,amenorrhea,overweight,hirsutism,endometrial hyperplasia and even canceration.Abnormal secretion of gonadotropin,development of hyperandrogenemia and ovarian dysfunction may be major causes of neuroendocrine dysfunction in PCOS.
出处
《医学综述》
2010年第18期2806-2808,共3页
Medical Recapitulate
关键词
多囊卵巢综合征
雄激素
不孕
黄体生成素
Polycystic ovary syndrome
Androgen
Infertility
Luteinizing hormone