铁超负荷对重型β地中海贫血患儿生长发育的影响

Effect of Iron Overload in β-thalassemia Major Growth and Development of Children

目的探讨铁超负荷对重型β地中海贫血患儿生长发育的影响。方法对定期在我院输血的42例重型β地中海贫血患儿进行身高、体重、血红蛋白、血清铁蛋白测定,并与正常组比较。结果地贫组的身高、体重、Hb低于正常组,血清铁蛋白高于正常组。结论重型β地中海贫血患儿的生长发育落后与长期贫血及铁超负荷有关。

Objective To explore Iron overload in β-thalassemia major growth and development of children.Methods 42 children withβ-thalassemia major and who received blood transfusion therapy regularly were enrolled.Height,weight,hemoglobin,serum ferritin were measured,and compared with normal group.Results Thalassemia group of height,weight,Hb lower than the normal group,serum ferritin higher than the normal group.Conclusions Growth and development delay are common in children withβ-thalassemia major.This may be related to long-term anemia and iron overload related.