摘要
文章综述近年文献,探讨柴胡加龙骨牡蛎汤治疗失眠的机理。中医病机方面,柴胡加龙骨牡蛎汤调和阴阳,宣畅化郁,助阳入阴,主治气郁型失眠;生理机制方面,柴胡加龙骨牡蛎汤被证明能调节下丘脑-垂体-肾上腺轴以及大脑单胺类神经递质,并对抑郁和焦虑行为均具调节作用。
Based on the recent published articles in review,the mechanism of Bupleurum Falcatum plus Dragon Bone and Oyster Shell Decoction（CJLM） on insomnia was discussed.In TCM pathogenesis,the CJLM governs QI stagnated insomnia,which regulates ＂Yin＂ and ＂Yang＂,regulates ＂Qi＂ stagnation and assists ＂Yang＂ to dive into ＂Yin＂.In the empirical studying,the CJLM is proved to regulate the hypothalamic-pituitary-adrenal axis and the monoamine neurotransmitters,as well as to harmonize the behaviors with depression and anxiety.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第8期1887-1888,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家"十一五"科技支撑计划(No.06BAI13B06-2)
关键词
柴胡加龙骨牡蛎汤
失眠
机理
Bupleurum Falcatum plus Dragon Bone and Oyster Shell Decoction（CJLM）
Insomnia
Mechanism
