分子识别材料D-萘普生印迹聚合物的制备与结构性能

Molecular Recognition Material of D-Naproxen Imprinted Polymers' Preparation and Their Microstructure and Properties

以D-萘普生为目标分子,采用差示紫外吸收光谱法研究了萘普生分子与功能单体间的作用力性质,确证了萘普生与丙烯酰胺通过氢键和离子键方式自组装形成超分子复合物。按不同的溶剂(致孔剂)用量合成了一组分子印迹聚合物材料,利用红外光谱对产物结构进行了分析,表明合成的产品具有所需的特征结构。首次使用透射电镜表征了分子印迹聚合物的微观形貌特征,阐明了溶剂的致孔作用机理,并结合吸附动力学研究了该材料的网孔结构对吸附速率的影响。根据选择性吸附实验的结果计算了所合成材料的特异吸附容量和印迹指数,其中,印迹指数最高达3.756。

A template molecule of D-naproxen was selected as the target. A differential ultraviolet absorption spectrum analysis method was designed to verify the nature of molecular interaction between naproxen and functional monomer. The facts proved that supra-molecular complex is formed by self-assembly through the non-covalent,including：hydrogen bonding and ionic bond. A group of molecular imprinted polymers （MIP）,synthesized in different amount of solvent,were analyzed by infrared spectra. It shows that these products have the necessary characteristics of the structure. The transmission electron microscopy was firstly used to observe the morphology of MIP,by which the pore-forming mechanism and the effect of the solvent were investigated. And those MIP were also tested in the adsorption kinetics experiments to testify the influence of morphology factors on the materials＇ adsorption properties. According to the calculation results of the selectivity assay for the synthetic MIP,the specific absorption capacity index and the imprint factor were obtained. It was up to 3.756.