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红细胞膜脂质与急性冠脉综合征斑块易损性的相关性研究 被引量：1

Relationship Between Lipid Content of Erythrocyte Membranes and Plaque Vulnerability of Acute Coronary Syndrome
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摘要 斑块的易损性是急性冠脉综合征主要病理生理机制。而斑块内出血和新生血管的形成在易损斑块的形成中起着重要的作用,这其中红细胞膜脂质可能发挥着巨大的作用,它们通过不同的机制使斑块从稳定发展为不稳定。 Plaque vulnerability is the main pathophysiological mechanism of acute coronary syndrome.Intraplaque hemorrhage and angiogenesis are key in the development of vulnerable unstable atherosclerotic plaque.They may promote the transition from a stable to an unstable lesion.
作者 潘令新 徐岩
机构地区 安徽医科大学第一附属医院心内科
出处 《心血管病学进展》 CAS 2010年第5期694-697,共4页 Advances in Cardiovascular Diseases
关键词 急性冠脉综合征 红细胞膜 胆固醇 磷脂 易损斑块 acute coronary syndrome erythrocyte membranes cholesterol phospholipids vulnerability plaque
分类号 R541.1 [医药卫生—心血管疾病]
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参考文献20

  • 1Valgimigli M,Agostoni P,Serruvs PW.Acute coronary syndromes:an emphasis shift from treatment to prevention,and the enduring challenge of vulnerable plaque detection in the cardiac catheterization laboratory[J].J Cardiovasc Med (Hagerstown),2007,8(4):221-229.
  • 2Kolodgie FD,Virmani R,Burke AP,et al.Pathologic assessment of the vulnerable human coronary plaque[J].Heart,2004,90(12):1385-1391.
  • 3Arbustini E,Morbini P,D'Armini AM,et al.Plaque composition in plexogenic and thromboembolic pulmonary hypertension:the critical role of thrombotic material in pultaceous core formation[J].Heart,2002,88(2):177-182.
  • 4Kolodgie FD,Gold HK,Burke AP,et al.Intraplaque hemorrhage and progression of coronary atheroma[J].N Engl J Med,2003,349(24):2316-2325.
  • 5Tabas I.Consequences of cellular cholesterol accumulation:basic concepts and physiological implications[J].J Clin Invest,2002,110(7):905-911.
  • 6Tziakas DN,Kaski JC,Chalikias GK,et al.Total cholesterol content of erythrocyte membranes is increased in patients with acute coronary syndrome:a new marker of clinical instability[J]? J Am Coll Cardiol,2007,49(21):2081-2089.
  • 7Pasterkamp G,Virmani R.The erythrocyte:a new player in atheromatous core formation[J].Heart,2002,88(2):115-116.
  • 8Takaya N,Yuan C,Chu B,et al.Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events:a prospective assessment with MRI-initial results[J].Stroke,2006,37(3):818-823.
  • 9Altaf N,MacSweeney ST,Gladman J,et al.Carotid intraplaque hemorrhage predicts recurrent symptoms in patients with high-grade carotid stenosis[J].Stroke,2007,38(5):1633-1635.
  • 10Kolodgie FD,Narula J,Yuan C,et al.Elimination of neoangiogenesis for plaque stabilization:is there a role for local drug therapy[J]? J Am Coll Cardiol,2007,49(21):2093-2101.

同被引文献24

  • 1张建华,徐岩,陈旭华,伍梦佐,程自平,陈斌.红细胞膜总胆固醇含量与急性冠状动脉综合征的相关性研究[J].中华临床医师杂志（电子版）,2011,5(11):3164-3169. 被引量：4
  • 2Xiao JJ, Chen YH. Prevalence of cardiovascular diseases in China [J]. Front Med China, 2010,4(1): 16 -20.
  • 3Wagsater D, Zhu C, Bjfirkegren J, et al. MMP-2 and MMP -9 are prominent matrix metalloproteinases during atherosclerosis develop- ment in the Ldlr(-/-)Apob(100/100) mouse[J]. Int J Mot Med,2011,28(2) : 247 -253.
  • 4Boldt HB, Bale LK, Resch ZT, et al. Effects of mutated pregnancy - associated plasma protein - a on atherosclerotic lesion development in mice[J]. Endocrinology,2013,154( 1 ) : 246 -252.
  • 5Lin HL, Xu XS, Lu HX, et al. Pathological mechanisms of erythro- cyte- induced vulnerability of atherosclerotic plaques[ J ]. Med Hy- potheses,2008,70( 1 ) : 105 - 108.
  • 6Kim - Shapiro DB, Schechter AN, Gladwin MT. Unravelling the re- actions of nitric oxide, nitrite, and hemoglobin in physiology and ther- apeutics[ J]. Arterioscler Thromb Vasc Biol, 2006, 26 (4) : 697 - 705.
  • 7Gossl M, Versari D, Hildebrandt HA, et al. Segmental heterogeneity of vasa vasorum neovascularization in human coronary atherosclerosis [ J]. JACC Cardiovasc Imaging,2010,3 ( 1 ) : 32 - 40.
  • 8Kolodgie FD, Burke AP, Nakazawa G, et al. Free cholesterol in ath- erosclerotic plaques: where does it come from? [ J]. Curr Opin Lipi- dol,2007,18 ( 5 ) : 500 - 507.
  • 9Lin HL, Xu XS, Lu HX, el al. Pathological mechanisms and dose dependency of erythrocyte induced vulnerability of athemsclerotic plaques[J]. J Mol Cell Cardiol, 2007, 43(3) : 272 -280.
  • 10Tziakas DN, Chalikias GK, Stakos D , et al. The role of red blood cells in the progression and instability of atherosclerotic plaque[ J]. Int J Cardiol, 2010,142(1) : 2 -7.

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心血管病学进展
2010年 第5期

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