经体循环脐血细胞移植治疗脑梗死机制及其疗效影响因素

Mechanisms of Systemically Transplanted HUCB Cell-mediated Recovery for Cerebral Infarction and Responsible Factors

本综述重点总结、回顾经体循环移植脐血细胞治疗脑梗死实验与临床研究结果,探讨其疗效机制。并就经体循环移植脐血细胞治疗脑梗死的优势、缺陷及影响其疗效的因素进行讨论。

This review summarizes relevant studies,discusses potential mechanisms of transplanted cell-mediated neuroprotection,and builds a case for the need to establish parameters that are critical for transplantation success.In particular,the article outlines the advantages and disadvantages of systemic delivery of human umbilical cord blood cells in the field of cellular transplantation for the treatment of ischemic stroke.